BRETT LAMBERT CV
Who is BRETT LAMBERT MAppSc, the PROPRIETOR and CHIEF SCIENTIST, of APPLIED ANALYTICAL LABORATORIES?
During year 12 chemistry, Mackay students were given the opportunity to learn laboratory skills in a sugar chemistry laboratory. It was here that Brett first met a major career influence – Dr Lionel Stock – who became Brett’s main mentor during the beginning of his chemistry undergraduate degree. Dr Stock’s PhD was supervised by Sir John Cornforth, the only Australian born Nobel Laureate in Chemistry (and Australian of the year, 1976).
After graduation Brett worked with Lionel at the Sugar School where he trained sugar chemists in analytical and inorganic chemistry. The Sugar School and Sugar Research Institute was populated with researchers with incredible skills.
Commencing his Post Graduate research in 1993, through the CSIRO Wendall Laboratory in Rockhampton, with access to organ baths, ELISA techniques & In vitro facilities, he set off making conjugates for vaccination of beef cattle against toxic Pimelea sp. plants. Free access to all manner of spectroscopic techniques made his post graduate research very rewarding. Supervised by Graham Pegg (retired) Deputy Vice Chancellor (Research), Central Queensland University and Michael D’Occhio, currently Professor of Food Security at UQ – Gatton, being a stickler for a vigorous scientific process was ingrained.
Upon achieving his MAppSc, (and following a year with Queensland Dept of Natural Resources), Brett commenced work with the Astra Zeneca funded pharmaceutical research facility at Griffith University (currently known as The GRIDD). The project used high throughput screening of rainforest plant and Great Barrier Reef coral extracts to screen for pharmaceutical leads. Brett’s role was isolation and structural elucidation of the leads through use of many different types of chromatography as well as Nuclear Magnetic Resonance (NMR) and Mass Spectrometry (GC-MS and LC-MS).
Deciding not to transfer to work overseas with Astra Zeneca, Brett spent six years with his other passion: Bass playing in a hard-working rock band.
A part time consultancy led to Brett working at a Gold Coast based laboratory developing the Urinary pyrrole test in 2004. Testing of the USA Method showed distinct flaws and adaptations were made to make the test reliable and repeatable. The Pyrrole/pyrrolene-one is a waste product that is easily destroyed by heat and light. The current protocols of Applied Analytical Laboratory pyrrole sample collection, in Australia, are based on his development work.
Excited by the potential of this test in the understanding and management of mental health, in 2009 Brett left the consultancy to set up an independent laboratory with standards acceptable to work with University research projects. Since 2010 AAL have been involved in all University based projects exploring oxidative stress biomarkers, which has resulted in validation of the Urinary Pyrrole test with Dr Stephanie Fryar-Williams through strong control and patient cohort.
NOTE: No previous published work in the “Pyrrole” field had controls included to reference the pathological group.
AAL engaged NATA to commence an accreditation process. AAL complied with all the requirements above and beyond the expected standards. With changes to regulations during the accreditation period, TGA IVD classification and the compliance with laboratory standards of NATA, means AAL is fully approved to conduct the pyrroles in urine test.
AAL is the only laboratory to distinguish between pyrroles and urobilinogen in urine, and therefore provides measures for each. This opens a wide range of mental health applications. REF UROBILINOGEN.
Since 2010, Brett has led work to establish pyrroles in urine as an irrefutable measure of oxidative stress, and correlated with symptoms, a measure of severity of mental health and the response to treatment. The resulting science has opened many exciting research projects now in the pipeline. Brett is also leading fundamental research into the understanding of the chemical mechanism of the expression of elevated urinary pyrroles by conducting spectroscopic studies on synthetic analogues of a model system. Dissemination of findings to date will be in the “Science of Pyrroles in Urine “lecture in 2021. https://apanlabs.com/pyrrole-test/#pyrroles-in-urine-test
Profit from this lecture will fund further detailed biochemical research. As this is the only detailed research in this test, in the world, this funding is incredibly important for improving the care for mental health issues, worldwide.
Bio Balance Health has created this Science of Pyrroles in Urine lecture in conjunction with Brett Lambert. The lecture has been released, in October 2021, to all health professionals within the BBH online education platform. BBH and AAL websites have registration details. https://biobalance.org.au/events/dr-training-program/
In summary: Brett Lambert MSc. Principal of Applied Analytical Laboratories has done extensive research in novel drug discoveries, vaccination research and animal and plant chemistry. As all his work has been confidential, except for the papers produced listed on the AAL website, his work is not for public viewing. Brett worked with Astra Zeneca in the 1990’s on novel drug discoveries. His skill with the 800 MHz NMR machine, one of the largest in the Southern Hemisphere, located at the GRIDD, (ref…TO BE SUPPLIED BY THE GRIDD..) allowed him to produce research results not previously possible with smaller machinery.
Brett’s understanding of the possible value of this test through his daily interactions with doctors and their patients over the last 17 years and his over 80,000 tests place him in a unique position to drive this world leading research.
Mental health is a set of biochemical profiles which can be measured and managed.
If we give the body the fundamental materials, or components, that it needs to repair itself it will have the capacity for healing.
APPLIED ANALYTICAL LABORATORIES SHARE THESE CORE BELIEFS WITH BIO BALANCE HEALTH.
BBH bought this urine test to Australia in 2004.